The 1965 Fender Stratocaster, which he doused in lighter fluid and then set on fire at the Astoria in London in March 1967, is anticipated to fetch around Â£500,000 ($1million).
At the end of his show Hendrix set fire to the base of his Fender Stratocaster â€“ as the astonished audience looked on and petrified venue staff ushered the performer off. Hendrix injured himself and had to be taken to hospital with minor burns on his hands.
Hendrix did his burning guitar stunt twice during his career. The one up for auction is the only one still in existence.